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The reactivation of Ero1 by molecular oxygen generates reactive oxygen species (ROS) in the ER

They help regulate the balance between reduced glutathione (GSH) and oxidized glutathione (GSSG), which is crucial for normal cellular processes and signaling

Nature Communications, 2012

These findings reinforce the importance of continued monitoring, early detection, and intervention strategies to possibly mitigate the growing burden of vitamin B12 deficiency in both public and private healthcare settings ( 12 deficiency
