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The reactivation of Ero1 by molecular oxygen generates reactive oxygen species (ROS) in the ER

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They help regulate the balance between reduced glutathione (GSH) and oxidized glutathione (GSSG), which is crucial for normal cellular processes and signaling

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Nature Communications, 2012

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These findings reinforce the importance of continued monitoring, early detection, and intervention strategies to possibly mitigate the growing burden of vitamin B12 deficiency in both public and private healthcare settings ( 12 deficiency

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