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Treatment Protocol Begin with conservative dosing (200-300 mcg daily or 500 mcg twice weekly) and titrate based on response

Patients with severe renal or hepatic impairment whether dose adjustments or avoidance are necessary will depend on the pharmacokinetic data presented in the eventual retatrutide SmPC

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By reducing tyrosinase activity, glutathione effectively slows down the production of new melanin, preventing the formation of additional dark spots while allowing existing pigmentation to gradually fade