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Such connections do not imply a direct role in the execution of ferroptosis, and while important to document, should be distinguished from core regulators of iron-dependent lipid peroxidation, such as ACSL4, system x c - , and GPX4

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[11] It is not related to goose bumps, which result from muscle contractions, except that both occur in the area where the hair shaft exits the skin

Main regulator of iron absorption is Hepcidin Hepcidin protein is encoded by HAMP gene and secreted by liver Hepcidin name is because it is hepatocellular protein with bactericidal activities Hepcidin binds to the cellular iron efflux channel ferroportin causing its internalization and proteolysis, there by inhibiting the release of iron from intestinal cells and macrophages Thus hepcidin lowers plasma iron levels and conversely deficiency of hepcidin causes iron overload Transcription of hepcidin is increased by cytokines and iron and decreased by iron deficiency, hypoxia and ineffective erythropoiesis Reference