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Yet, although these studies focused on the nuclear and metabolic roles of MOTS-c, it can be inferred that MOTS-c polymorphisms can have a functional impact, including metabolism and adaptive responses

10.2217/fvl.11.6 [DOI] [PMC free article] [PubMed] [Google Scholar] Guilbault C., De Sanctis J

Glutamine, the most abundant amino acid in the bloodstream, undergoes glutaminolysis to form alpha-ketoglutarate, an intermediate of the TCA cycle, sustaining ATP levels as cellular energy and thus mitigating AMPK activation (Bodineau et al., 2022

doi: 10.3390/TOXICS13070605 Toxics 116
