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Awakawa, T

Additional findings include the presence of epithelial cell-derived proteins associated with ferroptosis in plasma exosomes from pSS patients, the potential involvement of complement C5 and C9 in ferroptosis, and variations in the levels of ferroptosis-related proteins in the exosomes being more reflective of epithelial cell pathology compared to plasma

Because TrxR1 and hTrx1 are present in human serum and they appear in high-molecular-weight complexes (Figure 5B, serum TrxR1 appeared mainly in high-molecular-weight complexes (between 130-170 kDa) when analyzed by non-reducing SDS-PAGE followed by Western blotting

BMC Genomics 16:120