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Keywords: ischemic stroke, peptides, peptide regulation, transcriptomic analysis, RNA-Seq, brain, neuroprotection 1

It has been demonstrated in melanoma cell lines that the direct transcriptional target of TGF-1-the Kruppel-like transcription factor GLI2 not only suppresses MITF through PKA/cAMP signaling 52 but also directly downregulates tyrosinase-related protein 2 (TRP2) by competitive inhibition of CREB 53

There is no evidence for a reversal of adrenal failure after hematopoietic cell transplantation in X-ALD [91]

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3beta-Nrf2 signal axis