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Acknowledgements We thank Mitch Brinkkemper, Marielle van Breemen, Jonne Snitselaar, and Tom Bijl for experimental support

A second family, BPC-157 and TB-500, targets tissue repair rather than the GH axis: BPC-157 is proposed to work through angiogenesis, nitric-oxide signaling, and anti-inflammatory activity, while TB-500 binds actin to promote cell migration, blood-vessel formation, and collagen deposition

Patients are involved in the trial design process from the outset, providing input on study protocols, patient information materials, and other aspects of the trial

FIGURE 2 Glu receptors are roughly divided into ionic and metabolic types