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The same dose of creatine pyruvate increased plasma creatine and pyruvate concentration, liver pyruvate, glycogen and glucose concentration, and mRNA expression of gluconeogenesis and glycogenesis enzymes in the liver before hatch or early post-hatch (124)

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Of these, only a small percentage originated from mitochondrial or endoplasmic reticulum membranes, and compared to whole hippocampus, mitochondrial content was nearly depleted which allowed identification of proteins previously not detected in proteomic analyses