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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

10.1016/j.ymeth.2016.08.016 [DOI] [PubMed] [Google Scholar] Hu Y, Shi G, Zhang L, Li F, Jiang Y, Jiang S, Ma W, Zhao Y, Songyang Z, Huang J (2016) Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX

This vitamin is essential for healthy brain function and can enhance concentration

Glutathione works with both of these nutrients to heal tissues and prevent damage from foreign substances