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The copper is what enables the biological activity GHK without copper has significantly reduced effect on gene expression and tissue repair

2008;294:H2646H2652

Variants are pathway-level: they don't predict response to any specific compound, but they describe the metabolic and longevity terrain a clinician is prescribing into

Unlike B12 deficiency, which produces recognisable neurological and haematological symptoms, excess vitamin B12 typically remains asymptomatic and is discovered incidentally during routine blood tests
