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Phosphorylation of the NFB inhibitor proteins, IB and IB, by IKK kinases causes their subsequent proteasomal degradation and promotes the translocation of NFB to the nucleus (275)
However, GSH has an overall negative charge at physiological pH, and mitochondria also exhibit an enormous negative membrane potential [57, 58]
Both exhibited lower hepatic GSH levels and GCL activity, which were prevented with hormone replacement [64]
