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In pro-inflammatory situations, this is a self-reinforcing cycle that contributes to oxidative and nitrosative stress, generating an inflammatory state (Alamdari et al

These protective effects are attributed primarily to their antioxidative, anti-inflammatory, and antiapoptotic properties, providing scientific support for the use of TCM in thyroid disease management

By promoting osteoblast activity and possibly balancing the bone remodeling process, MOTS-c could emerge as a novel target for addressing osteoporosis or age-related bone fragility (pending further research)

ER Signaling increased IL-17A production in th17 cells by upregulating IL-23R expression, mitochondrial respiration, and proliferation