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RIPK1 can be phosphorylated by IKK/, TAK1, and the downstream mitogen-activated protein kinaseactivated protein kinase (MK2), as well as the more recently identified kinases TBK1 and IKK
A systematic review and meta-analysis demonstrated that pacing interventions lead to a significant reduction in fatigue (Hedges g = -0.52) and an improvement in physical function among ME/CFS patients compared to no treatment or routine care [175]
doi: 10.1016/j.phrs.2014.08.002 94 ToughDFBorrowPSprentJ
