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It plays a crucial role in lipid oxidation and energy production by transporting long-chain fatty acids to the mitochondrial matrix, where they are oxidized ("burned") to release energy

In this review, we provide a comprehensive overview of the formation characteristics and underlying drug tolerant mechanisms of DTP cells, investigate the potential drugs for DTP (including preclinical drugs, novel use for old drugs, and natural products) based on different medicine models, and discuss the necessity and feasibility of anti-DTP therapy, related application forms, and future issues that will need to be addressed to advance this emerging field towards clinical applications

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