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This was a 15-year-old boy who presented with mental retardation, mild motor impairment, and partial deafness
Ando Y, Nyhlin N, Suhr O, Holmgren G, Uchida K, el Sahly M, Yamashita T, Terasaki H, Nakamura M, Uchino M, et al
Li P, Liu X, Dong ZM
While we show that ROS is necessary for the permanent growth arrest/senescence phenotype induced by p21, our studies do not exclude the importance of the initial growth arrest associated with p21's known cell cycle inhibitory functions
