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Blood levels rise across the first several weekly doses and settle near steady state after about four weeks. That is why the four-week hold matters: the full effect of a dose change is not visible in the first few days

Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40

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doi: 10.1016/j.ymgme.2004.04.005
