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Dietary intake: Vegetarians, vegans, and those who limit their daily consumption of animal products may have to consume more vitamin B12, as it is mainly present in foods of animal origin

Accumulating evidence establishes asparagine synthetase (ASNS) as a critical driver of malignant progression in solid tumors including prostate cancer, where it sustains tumorigenesis through dual metabolic reprogramming ( In PCa, glutamine serves as a critical upstream hub in ammonium metabolism, with tumors exhibiting profound metabolic rewiring to sustain proliferative and stress-adaptive demands

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Synthetic versions can be derived from rooster combs or engineered in a lab, and there are a variety of proprietary formulations available