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Description
A mild approach applied to an advanced case

3b) and comparison with synthetic reference peptides led to the identification of D- O -Leu-D-Ala ( m/z 202.1073, [M-H] ) and L- O -Val-L-Val ( m/z 216.1238, [M-H] ), thus matching the cleavage peptides of cereulides D- O -Leu-D-Ala-L- O -Val-L-Val tetradepsipeptide motif 18

Their de-differentiated phenotype suggests a potential to survive, engraft and trans-differentiate once transplanted into the liver

When supplements are used as part of a comprehensive treatment plan (with phototherapy or topical treatments), initial visible repigmentation often begins around 3 to 6 months
