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The aberrant cytoplasmic accumulation of TDP-43 facilitates the formation of PSTDP-43 complexes, markedly enhancing the process of protein condensation and stabilization

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7,8 Hearing loss related to carboplatin treatment is also observed, but the overall prevalence is lower (0%-25%)

GHK-Cu activates genes encoding collagen I, III, and elastin production while simultaneously downregulating matrix metalloproteinases (MMPs) the enzymes responsible for degrading periodontal ligament fibers in periodontitis