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Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
[DOI] [PubMed] [Google Scholar] Jin X, Yang X, Islam E, Liu D, Mahmood Q, Li H, Li J
Excess of glucocorticoid induces cardiac dysfunction via activating angiotensin II pathway
However, for drugs such as lithium, milnacipran, pregabalin, and gabapentin that are not metabolized or little metabolized, and that are eliminated by renal excretion, 10 half-life increases in proportion to the severity of the renal disease
