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Dermal thickness, defined as the distance from the epidermaldermal junction to the dermaladipose junction or to the loose connective tissue subjacent to the panniculus carnosus, respectively, were determined at five randomly selected sites per h.p.f., as previously described 65

PNP, an enzyme that is part of the nucleotide metabolism via degradation of deoxyguanosine, is involved in NR metabolism in mammalian cells by metabolizing NR to NAM

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