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Kirkpatrick et al., 2021

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and timosaponin AIII (Tim-AIII) derived from Anemarrhena asphodeloides Bunge have been shown to induce ferroptosis in NSCLC cells by inhibiting GPX4-related signalling pathways [193, 194]

Disruption of this exchange mechanism could perturb NADH/NAD + in both compartments and thus could affect cellular redox homeostasis and energy metabolism (Fig
