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doi: 10.1158/0008-5472.CAN-08-2903
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells
These findings are consistent with those for other antioxidant enzymes: for example, lack of peroxiredoxin 3, a mitochondrially localized antioxidant enzyme, also augments apoptotic signaling in some cell types (60)
