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Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration

This suggests that dopaminergic immunomodulation could contribute to the development of this disorder (Fig

In other words, these DHRs are either non-immune-mediated or immune-mediated allergic reactions ranging from IgE-mediated (type I), cytotoxic (type II), immune complex (type III), and cell-mediated (type IV) hypersensitivities, according to Gell-Coombs classification

The clearest signals are in eye disease using a drop formulation, such as neurotrophic keratopathy and dry eye [3] [4] , plus short-term infusion safety data in healthy volunteers [6]
