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In: Clinical applications of biomolecules in disease diagnosis: a comprehensive guide to biochemistry and metabolism

Copper uptake into cells Divalent copper ions arriving at the cell surface are reduced to monovalent copper icons catalyzed by STEAP proteins, two His-Met clusters in the extracellular amino terminus of CTR1 bind and maintain the reduced state of the copper, which is subsequently transported into the cell [30]

People who take medications regularly that decrease stomach acid production can also become deficient in vitamin B12 for this reason, whether they consume enough from their diets or not

Lewandowska M, Sajdak S, Lubiski J