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5.3 Crizotinib Mutations in RAS isoforms are a common occurrence in human cancers ( SCH51344, though not used clinically, led to the identification of crizotinib, a widely used dual Met/ALK inhibitor, as a potent inhibitor of MTH1 activity

Cell Mol Neurobiol 28:643652 Liu L et al (2015) Lycium barbarum polysaccharides protected human retinal pigment epithelial cells against oxidative stress-induced apoptosis
Mujafarkani, N., Agurokpon, D

We have no long-term safety data
