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Von herausragender Bedeutung fr Gesundheit und Lebensqualitt ist das Verhltnis von Radikalen und Radikalfngern und der aus einem Missverhltnis der beiden Stoffgruppen resultierende oxidative Stress sowie die Fhigkeit, Fremd- und Schadstoffe zu neutralisieren

The main protein transporter involved in pump resistance is the MDR-associated protein [141], an efflux pump that reduces intracellular drug levels
10.1038/sj.ejcn.1601943 63 MustacichD.PowisG

Specifically, RSR-activated ZAK signaling induces phosphorylation of INTS12, enhancing its interaction with CSB and promoting recruitment of the Integrator complex to lesion-stalled RNA polymerase II (Pol II)