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This study measured integration of 14C derived from nuclear testing in genomic DNA to assess the dynamics of oligodendrocyte generation in multiple sclerosis brain and found that most cells within remyelinating lesions were old, suggesting that surviving mature oligodendrocyes may have contributed to remyelination

Immunol 33:53961 [DOI] [PubMed] [Google Scholar] 21.Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA

Vomiting was noteable at 1 mg/day in the PRESTO-study, as was the occurrence of dyskinesias but such adverse reactions have not been described in other clinical trials like the LARGO-trial

For instance, neurons with longer axons and multiple synapses require more energy for axonal transport or long-term plasticity (Salehi et al., 2019c