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miR-122 can promote hepatic lipogenesis by inhibiting the liver kinase B1 (LKB1)/5 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway through direct targeting of sirtuin 1 (SIRT1) [291]

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1 A, 4 B, 4 C: aetiology: 7 alcohol-related, 1 primary biliary cirrhosis, 1 secondary biliary stenosis) and six healthy matched controls

Notably, the brain appears to be a major site for MPs/NPs deposition, and this enrichment may have a strong association with the initiation and progression of neurodegenerative disorders, including PD