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36 In people with type 2 diabetes and established cardiovascular disease, two years of low-dose semaglutide (0.5 or 1 mg) reduced the risk of a composite outcome of cardiovascular death, nonfatal myocardial infarction or nonfatal stroke by 26%, primarily driven by stroke reduction
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For a fuller discussion of the GLP-1 agonist mechanism, see our overview What Is Semaglutide
Ceramide as a mediator of non-alcoholic fatty liver disease and associated atherosclerosis
