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Therefore, a deeper understanding of the temporal aspects of TGF- signaling in radiation skin fibrosis would enable the development of targeted therapies that are administered at the most appropriate stages of the disease, thereby maximizing their efficacy and minimizing potential adverse effects

Rotate injection sites: To prevent tissue irritation, researchers may vary the injection locations, typically including the thigh, upper arm, and abdomen

2022;12(5):e059783

Given the essential role of redox homeostasis in physiological and pathophysiological conditions, modulating redox enzymes such as TrxR via the formation of stable and irreversible adducts has enormous consequences for several cellular processes and regulating intracellular reactive oxygen species (ROS)