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Decreased Collagen Production in Chronologically Aged Skin

Across in-vitro and in-vivo models, investigators have used GHK-Cu to examine wound repair, ECM turnover, oxidative stress responses, and neuro-related endpoints by measuring readouts such as collagen deposition, inflammatory markers, vascular responses, and gene-expression profiles

Although the APF peptide was found in moderately higher abundance in IC/BPS relative to control urine, our results show that the APF peptide was inconsistently present in urine, suggesting that its utility as a sole biomarker of IC/BPS may be limited