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Its ability to penetrate the BBB, its metabolic stability, and its significant efficacy in restoring cognitive and motor functions in animal models of AD and PD, likely through modulating the HGF/c-Met system, position it as a highly promising therapeutic candidate for these debilitating neurodegenerative diseases [2]
That bioavailability advantage is real and well documented
Some patients also report improved sleep quality within the first few weeks
Have also demonstrated hypotensive, spasmolytic, bradycardic, respiratory stimulant, and a depressant effect on higher cerebral centres in high doses
