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It has been demonstrated that mutant SOD1 accumulates in the mitochondrial membrane gap, thereby reducing the activity of the electron transport chain (ETC) complex

A recent overview article summarizing AOD 9604 research notes that in isolated chondrocyte cultures, AOD 9604 has been reported to promote proteoglycan and collagen production , and may influence differentiation of adipose-derived mesenchymal stem cells toward osteogenic lineages suggesting a possible role as a tool to study cartilage and bone matrix biology

J Nutr 2014;144:75864