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These include limited long-term human cell survival due to temperature and physiological disparities, immune rejection, and a lack of standardized protocols and evaluation metrics

In vivo real-time visualization of leukocytes and intracellular hydrogen peroxide levels during a zebrafish acute inflammation assay

Furthermore, novel mechanisms have been proposed for LA against specific toxins, for example, direct inactivation of secretory phospholipase A 2 in some snake venoms or enhancement of p-glycoprotein activity to prevent saxitoxin entry into the neuronal cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Hasselbalch B., Lassen U., Hansen S., Holmberg M., Srensen M., Kosteljanetz M., Broholm H., Stockhausen M.T., Poulsen H.S