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Description
Snider AP, Wood JR
GTP deficits with age and the corresponding deficits in substrate availability for optimal small GTPase function lead to failures in autophagy with inefficient clearance of protein aggregates, including A

H 2 O 2 molecules are further eliminated by catalase, which catalyzes decomposition of H 2 O 2 to H 2 O and O 2 or by thiol peroxidases, such as glutathione peroxidases and Prxs [91,92], which catalyze the reduction of H 2 O 2 and/or organic hydroperoxides to water and the corresponding alcohols, respectively [93]
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