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As phase II detoxification enzymes, arthropod GSTs confer pesticide resistance through direct metabolism or sequestration of pesticides and indirectly by providing protection against oxidative stress induced by synthetic pesticides [22]

The primary pathway for osteoblast destruction via ROS involves mitochondrial apoptosis [16], which occurs through increased membrane permeability, release of cytochrome c, and apoptosis-inducing factor [17]

IV therapy offers direct absorption for faster results