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Evidence suggests that the autonomic nervous system (ANS) is affected by dementia

CRAN.R-project.org/package=MuMIn (2019)

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Active Parkin ubiquitinates many mitochondrial proteins located in the outer membrane, matrix and inner membrane, such as voltage-dependent anion channel 1 and mitofusins (Mfn1 and Mfn2) [84, 85]
