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Similarly, in microglia mitochondria, levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) have been shown to be regarded as a marker of DNA/ RNA oxidation due to the lack of protection of mitochondrial DNA (mtDNA) by histone proteins and its own limited repair capacity (41)

Hypothyroidism: worldwide, the prevalence varies, but iodine deficiency is a common cause in Many regions
Cancer: a dendritic-cell brake on antitumour immunity
