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The mRNA expression levels of PGC-1, Nrf2 and TFAM in the periodontitis group decreased and showed a higher level of apoptosis (57), which clearly proved that the aggravation of mitochondrial OS might interfere with the enhancement of periodontal cell apoptosis in diabetic periodontitis

You might want to consider other ingredients AHAs and retinol that are currently more scientifically backed anti-aging ingredients

Glutathione plays a crucial role in a detoxification system that is fundamental in plants, mammals, and fungi

Ghanem et al
