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Description
In myeloid derived suppressor cells (MDSCs), serine/threonine kinase PIM1-mediated phosphorylation of STAT3 at the S727 site enhances STAT3 transcriptional activity and leads to increased PPAR expression, which in turn enhances FAO expression and promotes melanoma cell resistance to PD-L1 treatment [164]

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Dietary Sources and Supplementation L-Carnitine can be obtained from various dietary sources, particularly those rich in protein: For individuals who may need higher amounts of L-Carnitine, supplements are available and can be used to ensure adequate intake, especially for those with specific health conditions or increased energy demands
