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Proc Am Assoc Thorac Surg:79, 1999

Furthermore, these advantages contribute to a broader and more versatile therapeutic scope, which significantly drives research into the development of targeted delivery systems [85]

Furthermore, the protein disulfide isomerase (PDI) directly interacts with integrins, mediating disulfide-thiol exchange, resulting in conformational changes and activation (Popierlarski et al

However, because it is an autoimmune disease, extra treatments may be necessary, too, such as corticosteroids or immunosuppressants in serious instances, to handle inflammation and autoimmunity
