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Biol Psy 81:402410, 2017

Primary hyperalgesia after tissue injury is suggested to result from sensitization of primary afferent fibers, but sensitization to mechanical stimuli has been difficult to demonstrate

Wegovy was developed for weight management, where clinical trials showed that higher doses (up to 2.4 mg) worked better for appetite suppression and weight loss

In the cAMP second messenger system, a water-soluble hormone binds to its receptor in the cell membrane (Step 1 in Figure 1.5)