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Lithium aluminum hydride (7.50 g, 197.63 mmol) was added into a solution of 2,2-(propane-2,2-diylbis(sulfanediyl))diacetic acid (11.10 g, 49.55 mmol) in dry tetrahydrofuran (200 mL)

When mice were orally administered 50 mg/kg of this compound, MNAM production decreased by approximately 80% within 2 h

5-Amino-1MQ may be used in laboratory studies involving: All applications are limited to research settings only and do not imply any approved human or animal use

It is well established that metabolic changes drive microglial polarization, and a number of pathways, including hypoxia-inducible factor-1alpha (HIF-1), forkhead box P3 (FOXP3), and nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, have been implicated in facilitating these effects [73]