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Proton pump inhibitors and similar medications that lower stomach acid might decrease the absorption of vitamin B12 from food, but this is less of a concern when receiving B12 injections because they bypass the digestive system entirely

Chronic treatment with PARP inhibitors increased NAD + levels and mitochondrial respiration in 10-week-old mice and triggered UPR mt and increased mitochondrial respiration and lifespan in worms 109,257

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