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doi: 10.1104/pp.127.1.15

When choosing ice treatment, it is advised to apply the cold compress to the affected area several times during the day for up to 20 minutes at a time

Du PlessisJVanheelHJanssenCERoosLSlavikTStivaktasPIet al
Human StudiesWhat We Know Heres the catch: all of the research mentioned above has been done in animal models
