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Description
Over the past few years, it has been identified and proven that the enzyme matrix metalloproteinases (MMPs), members of a zinc-dependent endopeptidase family, play a crucial role in the cleavage of extracellular matrix during tissue remodelling and thus mediate the spread of cancer to other organs [359]

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Role of matrix metalloproteinases in the development of airway inflammation and remodeling

Liver homeostasis is maintained by midlobular zone 2 hepatocytes
