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AOD 9604 and Cartilage / Joint Research Interest in AOD 9604 later shifted toward cartilage repair and osteoarthritis models : In a collagenase-induced knee osteoarthritis (OA) rabbit model , weekly intra-articular injections of AOD 9604 (0.25 mg), with or without hyaluronic acid (HA), enhanced cartilage regeneration compared with saline controls

Systemic delivery of fracture-homing bone anabolics holds great promise as a therapeutic strategy in this regard

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