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Additionally, the absence of standardized testing methods for measuring oxidative stress in clinical settings hinders early diagnosis and the development of customized treatment plans

As a result, the SLP becomes thinner and stiffer

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Consistent with a moderate increase of these well-described changes in healthy aging, we observed significantly higher levels of malondialdehyde (MDA), a marker for circulating levels of lipid peroxides, in older adults compared to the levels of young subjects (means, young = 0.136, older adults = 0.158 mol/L, p -value 300 uM in older adults is within the range of what has been described as being associated with elevated cardiovascular risk compared to that of young subjects (El-Khairy et al., 2001)