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GABRA 1 and GABRB 2 polymorphisms are associated with Propofol susceptibility

doi: 10.1016/j.jtos.2017.05.011 303 MiYWeiCSunLLiuHZhangJLuoJet al

Int J Psychophysiol 60 : 8894

The phenyl groups of Phe260 and Phe649 undergo significant conformational changes upon SQ109 binding, and their phenyl ring rotates by 7 , forming a V-shaped structure, which matches with the adamantine group of SQ109
